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Also, the patient should be informed that a transient return of ovarian function (intermittent ovarian failure) is possible.

The diagnosis should not be made on the basis of a single FSH test because this causes a great deal of mental strain for young women. Tests reveal a hypergonadotropic-hypogonadic hormone profile (also referred to as primary hypogonadism), which is characterised by low oestradiol (E 2) levels ( 20 IU/l), low anti-Müllerian hormone (AMH) levels – 40 IU/l, recorded at least twice at an internal of 4-6 weeks, call for a diagnosis of premature ovarian failure. Tests reveal a hypergonadotropic-hypogonadic hormone profile